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SBSC Dipartimento di Scienze Biomediche Sperimentali e Cliniche

Gruppo Fisica Medica

Coordinator of Research Team

Name…………………Franco Fusi………………………………………………………………………….

Position (Full Professor…….)……Associate Professor…………………………………………………………………………………

Name of Research Team/Laboratory …FISICA MEDICA (Medical Physics)…………………………………………

e-mail……………franco.fusi@unifi.it…………………………………………………………………………………….

telephone number……+39055278430……………………………………………………………………………..

 

 

 

Brief biographical sketch of the

DATE AND PLACE OF BIRTH: Dec 08, 1956, Florence, Italy
EDUCATION:

Degree in physics (University of Florence, 1983) ( 110/110 marks).
National Research Council (CNR) Fellowship from 1981 to 1983 at the Dept. of Pharmacology,  University of Florence
CNR-Fellowship at the Institute of Quantum Electronics of CNR from 1983 to 1990, then researcher at the same Institute.
Researcher at the Physiopathology dept., University of Florence since January 1996, now Professor of Applied Physics at the School of Life Sciences
SCIENTIFIC RESPONSIBILITY:

Expert member for CNR in Italian Electrotechnical Committee.  Group n.76 Laser Instrumentation and n.86 Optical fibers from 1993 to 1996.
Head of Microscopy Lab of Laser Medical Centre (CLAM), Florence, since 1994 
Scientific coordinator of CLAM, since 1995.
Member of the Directive Committee  of the Italian Society for Photobiology from 2004 to 2013
Councilor of CISPIM Center for Preclinical Study on Molecular Imaging of Florence University since 2008
Director of the School of Health Physics at Florence University From 2009 to 2011
Director of the School of Medical Physics at Florence University since 2014
President of the National Conference of Directors of Speciality Schools of Medical Physics, since 2014

Member of the Directive Committee of the Italian Medical Physics Association since 2015

In 2015 was among the founders of Probiomedica srl, a spin-off of the University of Florence devoted to innovative optical devices to perform non-invasive phototherapy against Helicobacter pylori.

Member of the following Scientific Societies

1) European Society for Photobiology.

                2) Italian Society of Medical Physics

                3) Italian Society of Photobiology

 

Member of the editorial board of the following Journals

1) European Journal of Medical Physics

 

 

Research Team

1)      Stefania PALLOTTA, 03/09/1961, Associate Professor

2)      Giovanni ROMANO, 14/06/1973, Associate Professor

3)      Cinzia TALAMONTI, 30/12/1965, Associate Professor

4)      Francesco RANALDI, 30/10/1963, Researcher

5)      Monica Monici,  02/09/1956, Researcher in Joint research labs with industrial partner

6)      Francesca Cialdai, 11/11/1981, Researcher in Joint research labs with industrial partner

7)      Silvia Calusi, 12/04/1980 post doc fellow

8)      Paola Faraoni, post doc fellow

9)      Alessio Gnerucci, 23/10/1979 ,post doc fellow

10)   Felicia Menicucci, phD

11)   Elettra Sereni, 06/02/1985,  PhD

12)   Leonardo Vignali, 16/06/1984, PhD

13)   Mattia Belli,  boursary

 

 

Current research interests  :

i)                    biomedical optics and photobiology;

ii)                   photophysics of biomolecules;

iii)                 design of phototherapy units;

iv)                 nanostructured chromophores based on gold nanoparticles for photothermal therapy

v)                   Physical stress on biological tissues

vi)                 Imaging with photon and charged particles

vii)               Photon and electron beam dosimetry

 

Current / recent sources of funding

1)      CAPSULIGHT “Ingestible capsule for phototherapy treatment of Helicobacter Pylori infection” Fas-Salute, Tuscany Region…(2014)

2)      SINERGY -  Multidisciplinary industrial development of multifunctional nanostructured innovative materials, Tuscany Region  (2013)

3)      RITMI – Riparazione dei Tessuti in Microgravità ASI N. 2013-090-R.O (2013)

4)      IPERNANO - Targeted magneto-optical carriers for tumor theranosis” Tuscany Region  (2011)………...

 

 

 

10 best publications of the last 5 years

  • Monici M, Cialdai F, Ranaldi F, Paoli P, Boscaro F, Moneti G, Caselli A. Effect of IR laser on myoblasts: a proteomic study. Mol Biosyst. Jun;9(6):1147-61. doi: 10.1039/c2mb25398d (2013)
  • Scaringella, M., Brianzi, M., Bruzzi, M., Bucciolini, M., Carpinelli, M., Cirrone, G. A. P., Pallotta S. Talamonti C & Pugliatti, C. The PRIMA (PRoton IMAging) collaboration: Development of a proton computed tomography apparatus. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 730, 178-183. (2013).
  • Scaringella, M., Bruzzi, M., Bucciolini, M., Carpinelli, M., Cirrone, G. A. P., Civinini, C.,Pallotta S. Talamonti C & Randazzo, N. A proton computed tomography based medical imaging system. Journal of Instrumentation, 9(12), C12009. . (2014)
  • Cavigli L. , de Angelis M.,Fulvio Ratto,Paolo Matteini,Francesca Rossi,Sonia Centi,Franco Fusi,Roberto Pini
    Size Affects the Stability of the Photoacoustic Conversion of Gold Nanorods
    Journal of Physical Chemistry. c, 118: 16140-16146 doi: 10.1021/jp502647p  (2014) 
  • Tatini F., Landini I.,Federica  Scaletti,Lara  Massai,Sonia  Centi,Fulvio  Ratto,Stefania  Nobili,Giovanni Romano,Franco  Fusi,Luigi  Messori,Enrico  Mini,Roberto  Pini
    Size dependent biological profiles of PEGylated gold nanorods
    Journal of Materials Chemistry. B  2: 6072-6080  doi: 10.1039/C4TB00991F (2014)          
  • Maier JAM, Cialdai F, Monici M, and Morbidelli L.  The Impact of Microgravity and Hypergravity on Endothelial Cells, Review Article. In: HOW MICROGRAVITY AFFECTS THE BIOLOGY OF LIVING SYSTEMS, Bizzarri M, Monici M, and van Loon JWA Eds. Hindawi Publishing Corporation, BioMed Research International, Volume 2015, Article ID 434803, 13 pages, doi:10.1155/2015/434803  (2015)
  • Ratto, F., Witort, E., Tatini, F., Centi, S., Lazzeri, L., Carta, F., Lulli, M., Vullo, D., Fusi, F., Supuran, C. T., Scozzafava, A., Capaccioli, S. and Pini, R.
    Plasmonic Particles that Hit Hypoxic Cells.
     Adv. Funct. Mater., 25: 316–323.  , doi: 10.1002/adfm.201402118      (2015)                    
  • Tortora  G., B. Orsini ; P. Pecile ; A. Menciassi ; F. Fusi ; G. Romano
    An Ingestible Capsule for the Photodynamic Therapy of Helicobacter pylori infection
    -IEEE/ASME Transactions on Mechatronics 21 (4), 7422794, pp. 1935-1942 (2016)        
  • Gnerucci, A., Romano, G., Ratto, F., Centi, S., Baccini, M., Santosuosso, U., Pini R. & Fusi, F.. Statistical detection of nanoparticles in cells by darkfield microscopy. Eur J Med Phys, 32(7), 938-943. (2016)
  • Arilli, C.; Talamonti, C.; Marrazzo, L.; Casati, M.; Compagnucci, A.; Calusi, S.; Fedeli, L.; Livi, L.; Pallotta, S. (2016). Reproducibility and sensitivity of IQM: A real-time monitoring device for complex radiotherapy treatments. PHYSICA MEDICA, vol. 32, pp. 1-2, ISSN:1120-1797

Previous research experiences

Autofluorescence microscopy and spectroscopy, phototherapy of neonatal jaundice

 

Main scientific contributions

- New Phototherapy set-up for phototherapy of Neonatal Jaundice

- Photophysical model for photoisomerization of bilirubin.

- Multispectral imaging autofluorescence microscopy for discrimination of tissues..

- Development of an ingestible lighting capsule for eradication of Helicobacter pylori infection

- Development of photon and proton device

-

 

 

PATENTs:

  • "Ingestible capsule for treating gastric infections, in particular for treating H.Pylori infections" European Patent EP2496306B1 Sept 12, (2012). and USA US 9138593 (2014)
  • "Assembly comprising an absorber of near infrared (nir) light covalently linked to an inhibitor of carbonic anhydrase " WO2014136076 (2014)
  • Italian Patent (FI2006A000167- “Apparato e metodo per la determinazione di dose assorbita in simulazioni di trattamenti radioterapici”)
  • “Bidimensional dosimetric detector USA - US8563936”  and  ITA (“Rilevatore dosimetrico bidimensionale” FI2006A000166.

 

 

Collaborations

 

CNR IFAC, Sesto Fiorentino, Florence  Roberto Pini, Fulvio Ratto

Scuola Superiore Sant’-Anna, Pisa, Biorobotics Institute, Arianna Menciassi

CNR NANO  Pisa, Francesco Ghetti, Antonella Sgarbossa

 

University of Florence, Enrico Mini, Luigi Messori,

University of Padova, Elena Reddi, Giorgia Miolo

University of Brescia, Prof. Calzavara Pinton

CNR IPCF Bari, Massimo Trotta

 

INFN

Dept. Physics University of Florence

Sichuan Cancer Hospital & Institute Prof LANG JINYI

 

 

 
ultimo aggiornamento: 24-Ott-2017
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