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SBSC Dipartimento di Scienze Biomediche Sperimentali e Cliniche

Attivita' di ricerca

ATTIVITA’ DI RICERCA

Il Dottorato di ricerca in scienze biomediche prevede, per sua natura, un percorso largamente interdisciplinare anche per quanto riguarda la ricerca. Lungo tale percorso, ogni studente viene a contatto con apporti provenienti da tematiche e discipline diverse che ne arricchiscono la visione prospettica anche per quanto riguarda le specifiche ricerche in cui è impegnato. Gli studenti del Dottorato in Scienze biomediche sono tenuti a frequentare continuativamente i laboratori su cui insistono i gruppi di ricerca a cui fanno riferimento. Nel corso dei tre anni del dottorato gli studenti acquisiscono progressivamente piena autonomia per quanto riguarda l’esecuzione delle attività sperimentali oltre alla capacità di discutere con i rispettivi tutor dei risultati delle ricerche effettuate del loro significato e degli sviluppi delle stesse.La partecipazione a corsi di aggiornamento, meeting scientifici e congressi e la frequente visita di laboratori italiani e stranieri per lo sviluppo delle attività di ricerca contribuiscono al percorso di maturazione scientifica degli studenti. La piena partecipazione dei dottorandi alle attività di ricerca delle unità di riferimento è testimoniata dai numerosissimi lavori scientifici pubblicati da tali unità in cui compaiono i nomi dei dottorandi spesso in grande evidenza a testimonianza del ruolo svolto nelle relative ricerche.

 

Selezione di lavori scientifici a cui hanno partecipato a pieno titolo gli studenti del Dottorato in Scienze biomediche a partire dal XXXI ciclo (2015-18)

  1. Lazzeri E, Angelotti ML, Peired A, Conte C, Marschner JA, Maggi L, Mazzinghi B, Lombardi D, Melica ME, Nardi S, Ronconi E, Sisti A, Antonelli G, Becherucci F, De Chiara L, Guevara RR, Burger A, Schaefer B, Annunziato F, Anders HJ, Lasagni L Romagnani P. Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury. Nat Commun. 2018, 9:1344.
  2. Romoli S, Angelotti ML, Antonelli G, Kumar Vr S, Mulay SR, Desai J, Anguiano Gomez L, Thomasova D, Eulberg D, Klussmann S, Melica ME, Conte C, Lombardi D, Lasagni L, Anders HJ, Romagnani P. CXCL12 blockade preferentially regenerates lost podocytes in cortical nephrons by targeting an intrinsic podocyte-progenitor feedback mechanism. Kidney Int. 2018, 94:1111-26.
  3. Krausz C, Cioppi F, Riera-Escamilla A. Testing for genetic contributions to infertility: potential clinical impact. Expert Rev Mol Diagn. 2018, 18:331-346.
  4. Cioppi F, Riera-Escamilla A, Manilall A, Guarducci E, Todisco T, Corona G, Colombo F, Bonomi M, Flanagan CA, Krausz C. Genetics of ncHH: from a peculiar inheritance of a novel GNRHR mutation to a comprehensive review of the literature. Andrology. 2018 Dec 21 doi: 10.1111/andr.12563.
  5. M. Merli, M. Moscatelli, G. Mariotti, U. Pagliaro, E. Raffaelli, M. Nieri Comparing membranes and bone substitutes in a one-stage procedure for horizontal bone augmentation. Three-year post-loading results of a double-blind randomised controlled trial. Eur. J. Oral Implantol. 2018, 11:441-52.
  6. B. Fischer, C. Masucci, A. Ruellas, L. Cevidanes, V. Giuntini, M. Nieri, C. Nardi, L. Franchi, J.A. Jr McNamara, E. Defraia) Three-dimensional evaluation of the maxillary effects of two orthopaedic protocols for the treatment of Class III malocclusion: A prospective study. Orthod. Craniofac. Res. 2018, 21:248-57.
  7. M. Merli, M. Moscatelli, U. Pagliaro, G. Mariotti, I. Merli, M. Nieri Implant prosthetic rehabilitation in partially edentulous patients with bone atrophy. An umbrella review based on systematic reviews of randomised controlled trials. Eur. J. Oral Implantol. 2018, 11:261-80.
  8. L. Barbato, N. Baldi, A. Gonnelli, M. Duvina, M. Nieri, P. Tonelli) Association of smoking habits and height of residual bone on implant survival and success rate in lateral sinus lift: A Retrospective Study. J. Oral Implantol. 2018, 44:432-8.
  9. L. Franchi, M. Nieri, J.A. Jr McNamara) Diagnostic reliability of the objective cervical vertebral maturation method for the mandibular growth peak. Eur. J. Orthod. 2018, 40:452-3.
  10. G. Fabbri, R. Sorrentino, G. Cannistraro, F. Mintrone, L. Bacherini, R. Turrini, T. Bombardelli, M. Nieri, M. Fradeani Increasing the vertical dimension of occlusion: A multicenter retrospective clinical comparative study on 100 patients with fixed tooth-supported, mixed, and implant-supported full-arch rehabilitations. Int. J. Periodontics Restorative Dent. 2018, 38:323-35.
  11. M.S. Tonetti, P. Cortellini, G. Pellegrini, M. Nieri, D. Bonaccini, M. Allegri, P. Bouchard, F. Cairo, G. Conforti, I. Fourmousis, F. Graziani, A. Guerrero, J. Halben, J. Malet, G. Rasperini, H. Topoll, H. Wachtel, B. Wallkamm, I. Zabalegui, O. Zuhr. Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession: Randomized trial assessing non-inferiority in root coverage and superiority in oral health-related quality of life. J. Clin. Periodontol. 2018, 45:78-88.
  12. A.L. Iorio, V. De Gregorio, O. Fantappiè, G. Laffi, M. de Martino, C. Pisano, L. Genitori, I. Sardi. Aldoxorubicin and Temozolomide combination in a xenograft mice model of human glioblastoma. Oncotarget. 2018, 9:34935-44.
  13. M. Da Ros, V. De Gregorio, A.L. Iorio, L. Giunti, M. Guidi, M. de Martino, L. Genitori, I. Sardi. Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier. Int. J. Mol. Sci. 2018, 19(10).
  14. Marino A, Real-Fernández F, Rovero P, Giani T, Pagnini I, Cimaz R,Simonini G. Anti-adalimumab antibodies in a cohort of patients with juvenile idiopathic arthritis: incidence and clinical correlations. Clin Rheumatol. 2018 Mar 5. doi: 10.1007/s10067-018-4057-7. [Epub ahead of print]
  15. Marino A, Giani T, Salvo G, Cimaz R. Iatrogenic effects of immune suppressants in the pediatric age. La Revue de médecine interne 39(2018)A51–A54.
  16. Marino A, Stagi S, Simonini G, Carli N, Caparello MC, Giani T, Pagnini I, DeMasi S, Cimaz R. Growth and body mass index in a cohort of patients with juvenile idiopathic arthritis: effects of second line treatments. Clin Exp Rheumatol. 2018 Jul 19. [Epub ahead of print]
  17. Marino A, Giani T, Cimaz R. Risks associated with use of TNF inhibitors in children with rheumatic diseases. Expert Rev Clin Immunol. 2018 Nov 19. doi:10.1080/1744666X.2019.1550359.
  18. E. Andreucci, S. Pietrobono, S. Peppicelli, J. Ruzzolini, F. Bianchini, A. Biagioni, B. Stecca, L. Calorini SOX2 as a novel contributor of oxidative metabolism in melanoma cells. Cell. Commun. Signal. 2018 16:87.
  19. J. Ruzzolini, S. Peppicelli, E. Andreucci, F. Bianchini, A. Scardigli, A. Romani, G. la Marca, C. Nediani, L. Calorini Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies. Nutrients. 2018 10.
  20. Lanzetta MM, Cozzi D, Addeo G,  Danti G, Canu L, De Filpo G, Ercolino T, Mannelli M, Miele V. Sindromi feocromocitoma/paraganglioma familiari: paraganglioma bilaterale del collo metastatico in paziente con mutazione del gene (SDH Familiar paraganglioma-pheochromocytoma syndromes: bilateral metastatic neck paraganglioma in a patient with gene SDHD-mutation). Il Giornale italiano di Radiologia Medica. 2018, 2:249-56
  21. Bonanni P, Zanella B, Santomauro F, Lorini C, Bechini A, Boccalini S. Safety and perception: What are the greatest enemies of HPV vaccination programmes? Vaccine. 2018, 36:5424-5429.
  22. Marino A, Giani T, Cimaz R. Risks associated with use of TNF inhibitors in children with rheumatic diseases. Expert Rev Clin Immunol. 2018 Nov 19. doi:10.1080/1744666X.2019.1550359.
  23. Palazzi L, Bruzzone E, Bisello G, Leri M, Stefani M, Bucciantini M, Polverino de Laureto P. Oleuropein aglycone stabilizes the monomeric α- synuclein and favours the growth of non-toxic aggregates. Sci. Rep. 8:8337 (2018).
  24. Leri M, Oropesa-Nuñez R, Canale C, Raimondi S, Giorgetti S, Bruzzone E, Bellotti V, Stefani M, Bucciantini M. Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity. Biochim. Biophys. Acta 1862: 1432-42 (2018).
  25. M. Leri, M. Ramazzotti, M. Vasarri, S. Peri, E. Barletta, C. Pretti, D. Degl'Innocenti. Bioactive compounds from Posidonia oceanica (L.) Delile impair malignant cell migration throught autophagy modulation Mar. Drugs. 2018, 16(4).
  26. Mannelli M, Canu L, Ercolino T, Rapizzi E, Martinelli S, Parenti G, De Filpo G, Nesi G. DIAGNOSIS OF ENDOCRINE DISEASE: SDHx mutations: beyond pheochromocytomas and paragangliomas. Eur J Endocrinol. 2018 178:R11-R17.
  27. Armignacco R, Cantini G, Canu L, Poli G, Ercolino T, Mannelli M, Luconi M. Adrenocortical carcinoma: the dawn of a new era of genomic and molecular biology analysis. J Endocrinol Invest 2018 4:499-507.
  28. Perge P, Decmann Á, Pezzani R, Bancos I, Fassina A, Luconi M, Canu L, Tóth M, Boscaro M, Patócs A, Igaz P. Analysis of circulating extracellular vesicle-associated microRNAs in cortisol-producing adrenocortical tumors. Endocrine. 2018 59:280-87.
  29. Buitenwerf E, Korteweg T, Visser A, Haag CMSC, Feelders RA, Timmers HJLM, Canu L, Haak HR, Bisschop PHLT, Eekhoff EMW, Corssmit EPM, Krak NC, Rasenberg E, van den Bergh J, Stoker J, Greuter MJW, Dullaart RPF, Links TP, Kerstens MN. Unenhanced CT imaging is highly sensitive to exclude pheochromocytoma: a multicenter study. Eur J Endocrinol. 2018 178:431-437.
  30. E.J. Cohen, R. Bravi, M.A. Bagni, D. Minciacchi Precision in drawing and tracing tasks: Different measures for different aspects of fine motor control. Hum. Mov. Sci. 2018, 61:177-88.
  31. R. Bravi, E.J. Cohen, A. Martinelli, A. Gottard, D. Minciacchi) The Less You Are, the More You Are Helped: Effect of Kinesio Tape on Temporal Coordination. Int. J. Sports. Med. 2018, 39:944-53.
  32. E. Quarta, G. Fulgenzi, R. Bravi, E.J. Cohen, S. Yanpallewar, L. Tessarollo, D. Minciacchi) Deletion of the endogenous TrkB.T1 receptor isoform restores the number of hippocampal CA1 parvalbumin-positive neurons and rescues long-term potentiation in pre-symptomatic mSOD1(G93A) ALS mice. Mol. Cell. Neurosci. 2018, 89:33-41.
  33. E. Maseroli, I. Scavello, B. Campone, V. Di Stasi, S. Cipriani, F. Felciai, V. Camartini, A. Magini, G. Castellini, V. Ricca, M. Maggi, L. Vignozzi. Psychosexual Correlates of Unwanted Sexual Experiences in Women Consulting for Female Sexual Dysfunction According to Their Timing Across the Life Span. J Sex Med. 2018,15:1739-1751.
  34. E. Maseroli, I. Scavello I, G. Rastrelli, E. Limoncin, S. Cipriani, G. Corona, M. Fambrini, A. Magini, EA Jannini, M. Maggi, L. Vignozzi. Outcome of Medical and Psychosexual Interventions for Vaginismus: A Systematic Review and Meta-Analysis. J Sex Med. 2018,15:1752-64.
  35. E. Limoncin, G.L. Gravina, F. Lotti, E. Maseroli, G. Ciocca, G. Corona, M. Maggi, Y. Reisman, G. Balercia, A. Lenzi, E.A. Jannini. The Masturbation Erection Index (MEI): validation of a new psychometric tool, derived from the six-item version of the International Index of Erectile Function (IIEF-6) and from the Erection Hardness Score (EHS), for measuring erectile function during masturbation. BJU Int. 2018 Sep 26. [Epub ahead of print]
  36. D. Mollaioli, S. Di Sante, E. Limoncin, G. Ciocca, G.L. Gravina, E. Maseroli, E. Fanni, L. Vignozzi, M. Maggi, A. Lenzi, E.A. Jannini. Validation of a Visual Analogue Scale to measure the subjective perception of orgasmic intensity in females: The Orgasmometer-F. PLoS One. 2018;13:e0202076.
  37. F. Lotti, E. Baldi, G. Corona, F. Lombardo, E. Maseroli, S. Degl'Innocenti, L. Bartoli, M. Maggi. Epididymal more than testicular abnormalities are associated with the occurrence of antisperm antibodies as evaluated by the MAR test. Hum Reprod. 2018 [Epub ahead of print]
  38. E. Maseroli, I. Scavello, L. Vignozzi. Cardiometabolic Risk and Female Sexuality-Part I. Risk Factors and Potential Pathophysiological Underpinnings for Female Vasculogenic Sexual Dysfunction Syndromes. Sex Med Rev. 2018; 6:508-524.
  39. E. Maseroli, I. Scavello, L. Vignozzi. Cardiometabolic Risk and Female Sexuality-Part II. Understanding (and Overcoming) Gender Differences: The Key Role of an Adequate Methodological Approach. Sex Med Rev. 2018; 6:525-534.
  40. J. Samavat, G. Cantini, F. Lotti, A. Di Franco, L. Tamburrino, S. Degl'Innocenti, E. Maseroli, E. Filimberti, E. Facchiano, M. Lucchese, M. Muratori, G. Forti, E. Baldi, M. Maggi, M. Luconi. Massive Weight Loss Obtained by Bariatric Surgery Affects Semen Quality in Morbid Male Obesity: a Preliminary Prospective Double-Armed Study. Obes Surg. 2018; 28:69-76.
  41. G. Camarlinghi, ME. Parisio, A. Antonelli, M. Nardone, M. Coppi, T. Giani, R. Mattei, GM. Maria Rossolini. (2018). Discrepancies in fosfomycin susceptibility testing of KPC-producing Klebsiella pneumoniae with various commercial methods. Diagnostic Microbiology and Infectious Disease. 2018, 10.1016/j.diagmicrobio.2018.07.014.
  42. C. Miceli, Y. Santin, N. Manzella, R. Coppini, A. Berti, M. Stefani, A. Parini, J. Mialet-Perez and C. Nediani Oleuropein aglycone protects against MAO-A-induced autophagy impairment and cardiomyocyte death through  activation of TFEB" Ox. Med. Cell Long. 2018 (Accepted)
  43. R. Oropesa-Nuñez, S. Keshavan, S. Dante, A. Diaspro, B. Mannini, C. Capitini, C. Cecchi, M. Stefani, F. Chiti, C. Canale Single cell force spectroscopy reveals the affinity of toxic and nontoxic protein misfolded oligomers for the cell membrane, its components and the extracellular matrix. Biophys. J. 2018 (Accepted).
  44. Cohen EJ, Bravi R, Minciacchi D The effect of fidget spinners on fine motor control. Sci Rep. 8(1):3144, 2018.
  45. Coppi M, Cannatelli A, Antonelli A, Baccani I, Di Pilato V, Sennati S, Giani T, Rossolini GM. A simple phenotypic method for screening of MCR-1-mediated colistin resistance. Clin Microbiol Infect. 2018, 24:201.e1-201.e3.
  46. Mori F, Angelucci C, Cianferoni A, Barni S, Indolfi G, Casini A, Mangone G, Materassi M, Pucci N, Azzari C, Novembre E. Increase of natural killer cells in children with liver transplantation-acquired food allergy. Allergol Immunopathol (Madr). 2018 Feb 15. pii: S0301-0546(18)30001-6.
  47. Ricci S, Masini M, Valleriani C, Casini A, Cortimiglia M, Grisotto L, Canessa C, Indolfi G, Lippi F, Azzari C. Reduced frequency of peripheral CD4+CD45RA+CD31+ cells and autoimmunity phenomena in patients affected by Del22q11 syndrome. Clin Immunol. 2018 Mar;188:81-84.
  48. Barzaghi F, Amaya Hernandez LC, Neven B, Ricci S, Primary Immune Deficiency Treatment Consortium (PIDTC) and the Inborn Errors Working Party (IEWP) of the European Society for Blood and Marrow Transplantation (EBMT). Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study. J Allergy Clin Immunol. 2018 Mar;141(3):1036-1049.e5.
  49. Graverini G, Piazzini V, Landucci E, Pantano D, Nardiello P, Casamenti F, Pellegrini-Giampietro DE, Bilia AR, Bergonzi MC. Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation.  Colloids Surf B Biointerfaces. 2018, 161:302-313
  50. Sassoli C, Vallone L, Tani A, Chellini F, Nosi D, Zecchi-Orlandini S. Combined use of bone marrow-derived mesenchymal stromal cells (BM-MSCs) and platelet rich plasma (PRP) stimulates proliferation and differentiation of myoblasts in vitro: new therapeutic perspectives for skeletal muscle repair/regeneration.Cell Tissue Res. 2018 Feb 5. doi: 10.1007/s00441-018-2792-3.
  51. Morelli A, Sarchielli E, Guarnieri G, Coppi E, Pantano D, Comeglio P, Nardiello P, Pugliese AM, Ballerini L, Matucci R, Ambrosini S, Castronovo G, Valente R, Mazzanti B, Bucciantini S, Maggi M, Casamenti F, Gallina P, Vannelli GB. Young Human Cholinergic Neurons Respond to Physiological Regulators and Improve Cognitive Symptoms in an Animal Model of Alzheimer's Disease. Front Cell Neurosci. 2017 11:339.
  52. Chellini F, Giannelli M, Tani A, Ballerini L, Vallone L, Nosi D, Zecchi-Orlandini S, Sassoli C. Mesenchymal stromal cell and osteoblast responses to oxidized titanium surfaces pre-treated with λ = 808 nm GaAlAs diode laser or chlorhexidine: in vitro study. Lasers Med Sci. 2017; 32(6):1309-1320.
  53. Domazetovic V, Marcucci G, Iantomasi T, Brandi ML, Vincenzini MT. Oxidative stress in bone remodeling: role of antioxidants. Clin Cases Miner Bone Metab. 2017, 14(2):209-216.2.
  54. Domazetovic V, Fontani F, Tanini D, D'Esopo V, Viglianisi C, Marcucci G, Panzella L, Napolitano A, Brandi ML, Capperucci A, Menichetti S, Vincenzini MT, Iantomasi T. Protective role of benzoselenophene derivatives of resveratrol on the induced oxidative stress in intestinal myofibroblasts and osteocytes. Chem Biol Interact. 2017, 275:13-21.
  55. Domazetovic V, Fontani F, Marcucci G, Iantomasi T, Brandi ML, Vincenzini MT. Estrogen inhibits starvation-induced apoptosis in osteocytes by a redox-independent process involving association of JNK and glutathione S-transferase P1-1. FEBS Open Bio. 2017, 7(5):705-718.
  56. E. Maseroli, I. Scavello, S. Cipriani, M. Palma, M. Fambrini, G. Corona, E. Mannucci, M. Maggi, L. Vignozzi. Psychobiological Correlates of Vaginismus: An Exploratory Analysis. J Sex Med. 2017;14:1392-1402.
  57. M. Reconditi, M. Caremani, F. Pinzauti, J. Powers, T Narayanan, G.J.M. Stienen, M. Linari, V. Lombardi, G. Piazzesi. Myosin filament activation in the heart is tuned to the mechanical task. Proc. Natl. Acad. Sci. USA, 114:3240-3245, 2017.
  58. Piccini P, Venturini E, Romano F, Di Maurizio M, De Filippi C, Azzari C, de Martino M, Galli L. Osteomyelitis and arthritis caused by Mycobacterium intracellulare: an underestimated diagnosis. Int J Tuberc Lung Dis 2017,21:1184-1185.
  59. Piccini P, Venturini E, Bianchi L, Baretti S, Filidei P, Paliaga L, Mazzoli F, Chiappini E, de Martino M, Galli L. The Risk of Mycobacterium tuberculosis Transmission from Pediatric Index Cases to School Pupils. Pediatr Infect Dis J 2017, 36:525-528.
  60. Venturini E, Tersigni C, Chiappini E, de Martino M, Galli L. Optimizing the management of children with latent tuberculosis infection. Expert Rev Anti Infect Ther 2017, 1-9.
  61. Chiappini E, Venturini E, Remaschi G, Principi N, Longhi R, Tovo PA, Becherucci P, Bonsignori F, Esposito S, Festini F, Galli L, Lucchesi B, Mugelli A, Marseglia GL, de Martino M; Italian Pediatric Society Panel for the Management of Fever in Children. 2016 Update of the Italian Pediatric Society Guidelines for Management of Fever in Children. J Pediatr 2017, 180:177-183.
  62. Sollai S, Ghetti F, Bianchi L, de Martino M, Galli L, Chiappini E. Infectious diseases prevalence, vaccination coverage, and diagnostic challenges in a population of internationally adopted children referred to a Tertiary Care Children's Hospital from 2009 to 2015. Medicine (Baltimore) 2017, 96:e6300.
  63. Chiappini E, Sollai S, de Martino M, Galli L. Malaria in Children Adopted from the Democratic Republic of the Congo. Emerg Infect Dis 2017, 23:721-722.
  64. Cinelli E, Iovino L, Mutolo D. ATP and astrocytes play a prominent role in the control of the respiratory pattern generator in the lamprey. J. Physiol.. 595: 7063-7079, 2017.
  65. Fusi L, Percario V, Brunello E, Caremani M, Bianco P, Powers J D, Reconditi M, Lombardi V and Piazzesi G. Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle. J Physiol 595, 1127–1142, 2017.
  66. Casamonti E, Vinci S, Serra E, Fino MG, Brilli S, Lotti F, Maggi M, Coccia ME, Forti G, Krausz C. Short-term FSH treatment and sperm maturation: a prospective study in idiopathic infertile men. Andrology. 5(3):414-422, 2017.
  67. Krausz C, Casamonti E. Spermatogenic failure and the Y chromosome. Hum Genet. 136(5):637-655, 2017.
  68. Paoloni V., Lione R., Farisco F., Halazonetis D.J., Franchi L., Cozza P Morphometric covariation between palatal shape and skeletal pattern in class II growing subjects. Eur J Orthod. 39(4): 371-376, 2017.
  69. Merli M, Bianchini E, Mariotti G, Moscatelli M, Piemontese M, Rappelli G, Nieri M. Ceramic vs composite veneering of full arch implant-supported zirconium frameworks: assessing patient preference and satisfaction. A crossover double-blind randomised controlled trial Eur J Oral Implantol. 2017, 10:311-322.
  70. Esposito M, Jacobs R, Nieri M. Editorial. Eur J Oral Implantol. 2017, 10 Suppl 1:2.
  71. Angelieri F, Franchi L, Cevidanes LHS, Gonçalves JR, Nieri M, Wolford LM, McNamara JA Jr. Cone beam computed tomography evaluation of midpalatal suture maturation in adults. Int J Oral Maxillofac Surg. 2017, 46(12):1557-1561.
  72. Nieri M, Tofani E, Defraia E, Giuntini V, Franchi L. Enamel defects and aphthous stomatitis in celiac and healthy subjects: Systematic review and meta-analysis of controlled studies. J Dent. 2017, 65:1-10.
  73. Cairo F, Barbato L, Tonelli P, Batalocco G, Pagavino G, Nieri M. Xenogeneic collagen matrix versus connective tissue graft for buccal soft tissue augmentation at implant site. A randomized, controlled clinical trial. J Clin Periodontol. 2017, 44(7):769-776.
  74. Merli M, Moscatelli M, Mariotti G, Motroni A, Mazzoni A, Mazzoni S, Breschi L, Nieri M. A Novel Approach to Bone Reconstruction: The Wafer Technique. Int J Periodontics Restorative Dent. 2017, 37(3):317-325.
  75. Merli M, Bernardelli F, Giulianelli E, Toselli I, Mariotti G, Nieri M.Peri-implant bleeding on probing: a cross-sectional multilevel analysis of associated factors. Clin Oral Implants Res. 2017, 28(11):1401-1405.
  76. Auconi P, Scazzocchio M, Caldarelli G, Nieri M, McNamara JA, Franchi L.Understanding interactions among cephalometrics variables during growth in untreated Class III subjects. Eur J Orthod. 2017, 39(4):395-401.
  77. Trombelli L, Minenna L, Toselli L, Zaetta A, Checchi L, Checchi V, Nieri M, Farina R. Prognostic value of a simplified method for periodontal risk assessment during supportive periodontal therapy. J Clin Periodontol. 2017, 44(1):51-57.
  78. E. Terzuoli, F. Finetti, F. Costanza, A. Giachetti, M. Ziche and S. Donnini Linking of mpges-1 and inos activates stem-like phenotype in egfr-driven epithelial tumor cells Nitric Oxide, 2017, 66:17-29.
  79. Maseroli E, Scavello I, Cipriani S, Palma M, Fambrini M, Corona G, Mannucci E, Maggi M, Vignozzi L. Psychobiological Correlates of Vaginismus: An Exploratory Analysis. J Sex Med. 2017, 14(11):1392-1402
  80. Corona G, Dicuio M, Rastrelli G, Maseroli E, Lotti F, Sforza A, Maggi M. Testosterone treatment and cardiovascular and venous thromboembolism risk: what is 'new'? J Investig Med. 2017 65(6):964-973.
  81. Corona G, Tirabassi G, Santi D, Maseroli E, Gacci M, Dicuio M, Sforza A, Mannucci E, Maggi M. Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis. Andrology. 2017, 5(4):671-678.
  82. Cohen EJ, Bravi R, Minciacchi D 3D Reconstruction of Human Movement in a Single Projection by Dynamic Marker Scaling. PLoS One. 12(10):e0186443, 2017.
  83. Bravi R, Cohen EJ, Martinelli A, Gottard A, Minciacchi D When Non-Dominant is Better than Dominant: Kinesiotape Modulates Asymmetries in Timed Performance during a Synchronization-Continuation Task. Front Integr Neurosci. 11:21, 2017.
  84. Cohen EJ, Quarta E, Bravi R, Granato A, Minciacchi D Neural Plasticity and Network Remodeling: From Concepts to Pathology. Neuroscience. 344:326-345, 2017.
  85. Dinu M, Pagliai G, SOFI F. A heart-healthy diet: recent insights and practical recommendations. Curr Cardiol Rep 2017, 19: 95.
  86. Dinu M, Abbate R, Gensini GF, Casini A, SOFI F. Vegetarian, vegan diets and multiple health outcomes: a systematic review with meta-analysis of observational studies. Crit Rev Food Sci Nutr 2017, 17: 3640-3649.
  87. Dinu M, Macchia D, Pagliai G, Gori AM, Cesari F, Marcucci R, SOFI F, Casini A. Symptomatic efficacy of buckwheat products in non-celiac gluten sensitivity (NCGS). Asia Pac J Clin Nutr 2017, 26: 630-636.
  88. Whittaker A, Dinu M, Cesari F, Gori AM, Fiorillo C, Becatti M, Casini A, Marcucci R, Benedettelli S, Sofi F. A khorasan wheat-based replacement diet improves risk profile of patients with type 2 diabetes mellitus (T2DM): a randomized controlled trial. Eur J Nutr 2017, 56: 1191-1200.
  89. SofiI F, Dinu M, Pagliai G, Marcucci R, Casini A. Validation of a literature-based adherence score to Mediterranean diet: the MEDI-LITE score. Int J Food Sci Nutr 2017, 68: 757-762.
  90. Cascella R, Evangelisti E, Bigi A, Becatti M, Fiorillo C, Stefani M, Chiti F, Cecchi C. Soluble Oligomers Require a Ganglioside to Trigger Neuronal Calcium Overload. J Alzheimers Dis. 2017, 60(3):923-938.
  91. Cascella R, Fani G, Capitini C, Rusmini P, Poletti A, Cecchi C, Chiti F. Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy. FASEB J. 2017, 31(12):5609-5624.
  92. Ghadami SA, Bemporad F, Sala BM, Tiana G, Ricagno S, Chiti F. FRET studies of various conformational states adopted by transthyretin. Cell Mol Life Sci. 2017, 74(19):3577-3598.
  93. Rashno F, Khajeh K, Capitini C, Sajedi RH, Shokri MM, Chiti F. Very rapid amyloid fibril formation by a bacterial lipase in the absence of a detectable lag phase. Biochim Biophys Acta. 2017, 865(6):652-663.
  94. Coppi M, Antonelli A, Giani T, Spanu T, Liotti FM, Fontana C, Mirandola W, Gargiulo R, Barozzi A, Mauri C, Principe L, Rossolini GM. Multicenter evaluation of the RAPIDEC® CARBA NP test for rapid screening of carbapenemase-producing Enterobacteriaceae and Gram-negative nonfermenters from clinical specimens. Diagn Microbiol Infect Dis. 2017, 88(3):207-213.
  95. Di Paola M, Sani C, Clemente AM, Iossa A, Perissi E, Castronovo G, Tanturli M, Rivero D, Cozzolino F, Cavalieri D, Carozzi F, De Filippo C, Torcia MG. Characterization of cervico-vaginal microbiota in women developing persistent high-risk Human Papillomavirus infection. Sci Rep. 2017, 7(1):10200
  96. Di Cesare Mannelli L, Tenci B, Micheli L, Vona A, Corti F, Zanardelli M, Lapucci A, Clemente AM, Failli P, Ghelardini C. Adipose-derived stem cells decrease pain in a rat model of oxaliplatin-induced neuropathy: Role of VEGF-A modulation. Neuropharmacology. 2017, 131:166-175.
  97. Clemente AM, Castronovo G, Antonelli A, D'Andrea MM,  Tanturli M, Perissi E, Paccosi S, Parenti A, Cozzolino F, Rossolini GM, Torcia MG. Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase. PLoS One. 2017, 12(6):e0178847.
  98. Castronovo G, Clemente AM, Antonelli A, D'Andrea MM, Tanturli M, Perissi E, Paccosi S, Parenti A, Cozzolino F, Rossolini GM, Torcia MG. Differences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases. PLoS One. 2017,12(1):e0170125.
  99. Serranti D, Indolfi G, Nebbia G, Cananzi M, D'Antiga L, Ricci S, Stagi S, Azzari C, Resti M; Italian Study Group for Treatment of Chronic Hepatitis C in Children. Transient Hypothyroidism and Autoimmune Thyroiditis in Children with Chronic Hepatitis C Treated with Pegylated-Interferon-α-2b and Ribavirin. Pediatr Infect Dis J. 2017
  100. Lodi L, Ricci S, Romano F, Ghiori F, Canessa C, Lippi F, Bianchi L, Azzari C. Newborn screening for PIDs using both TREC and KREC identifies late occurrence of B cells. Pediatr Allergy Immunol. 2017, 28(5):498-500
  101. Carloni I, Ricci S, Azzari C, Galletti S, Faldella G, de Benedictis FM. Fatal pertussis in infancy, Italy. J Infect. 2017, 75(2):186-189.
  102. Nieddu F, Moriondo M, De Vitis E, Ricci S, Indolfi G, Resti M, Vocale C, Landini MP, Sartor A, Azzari C; Italian group for the study of Invasive Pneumococcal Disease. PCV13 serotype decrease in Italian adolescents and adults in the post-PCV13 era: Herd protection from children or secular trend? Vaccine. 2017, 35(11):1544-1550
  103. Ricci S, Romano F, Nieddu F, Picard C, Azzari C. OL-EDA-ID Syndrome: a Novel Hypomorphic NEMO Mutation Associated with a Severe Clinical Presentation and Transient HLH. J Clin Immunol. 2017, 37(1):7-11.
  104. P. Nardiello, D. Pantano, A. Lapucci, M. Stefani and F. Casamenti Diet supplementation with hydroxytyrosol ameliorates brain pathology and restores cognitive functions in a mouse model of Aß deposition. J. Alz. Dis. 60:923-38, 2017
  105. C.D. Hart, A. Vignoli, L. Tenori, G.L. Uy , T.V. To, C. Adebamowo, S.M. Hossain, L. Biganzoli, E. Risi, R.R. Love, C. Luchinat, A. Di Leo Serum Metabolomic Profiles Identify ER-Positive Early Breast Cancer Patients at Increased Risk of Disease Recurrence in a Multicenter Population. Clin Cancer Res. 2017, 23-1422.
  106. D. Pantano, I. Luccarini, P. Nardiello, M. Servili, M. Stefani and F. Casamenti Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology in TgCRND8 mice. Br. J. Clin. Pharmacol. 2017, 83:54-62.
  107. L. Fusi, V. Percario, E. Brunello, M. Caremani, P. Bianco, J. D. Powers, M. Reconditi, V. Lombardi and G. Piazzesi Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle. J. Physiol. 2017, 595:1127–42.
  108. M. Caremani, F. Pinzauti, M. Reconditi, G. Piazzesi, G. Stienen, V. Lombardi, M. Linari The size and speed of the working stroke of cardiac myosin in situ. Proc. Natl. Acad. Sci. USA 2016, 113:3675-3680.
  109. Corsini I, Polvani S, Tarocchi M, Tempesti S, Marroncini G, Generoso M, Bresci C, Gozzini E, Bianconi T, Galli A, Dani C.Peroxisome proliferator-activated receptor-γ agonist pioglitazone reduces the development of necrotizing enterocolitis in a neonatal preterm rat model. Pediatr Res. 2017, 2:364-368.
  110. F. Sofi, M. Dinu, G. Pagliai, R. Marcucci and A. Casini Efficacy of Oral Validation of a literature-based adherence score to Mediterranean diet: the MEDI-LITE score. ‎Int. J. Food Sci. Nutr. 2017, 1-6.
  111. Stagi S, Cavalli L, Ricci S, Mola M, Marchi C, Seminara S, Brandi ML, de Martino M. Parathyroid Hormone Levels in Healthy Children and Adolescents. Horm Res Paediatr. 2015, 84(2):124-9.
  112. M.G. Gil, F. Pierucci, A. Vestri and E. Meacci Crosstalk between sphingolipids and vitamin D3: potential role in the nervous system. Br J Pharmacol. 2017, [Accepted article].
  113. F. Pierucci, M.G. Gil, A.Frati, A.Vestri, B.Ricci, E. Vannini, F. Luzzati, M. Caleo, P. Peretto and E. Meacci Vitamin D3 protects against amyloid β 1-42 peptide cytotoxicity in differentiated human neuroblastoma SH-SY5Y cells: a role for S1P/S1P1 axis. Neuropharmacology 2017, [Accepted article].
  114. I. Giangrandi, M. Dinu, G. Pagliai, F. Sofi and A. Casini Supplementation with Silymarin and S-Adenosyl-L-Methionine in Patients with Non Alcoholic Fatty Liver Disease – A Pilot Study. Alt. Integr. Med. 2016, 5:4.
  115. M. Dinu, D. Macchia, G. Pagliai, AM. Gori, F. Cesari, R. Marcucci, F. Sofi and A. Casini Symptomatic efficacy of buckwheat products in Non-Celiac Gluten Sensitivity Asia Pacific J. Clin. Nutr. 2016, doi: 10.6133/apjcn.072016.07.
  116. K. Petroka, M. Dinu, C. Hoover, A. Casini and F. Sofi Short-term exposure to a Mediterranean environment influences attitudes and dietary profile in U.S. College students: The MEDiterranean Diet in AMEricans (A-MED-AME) Pilot Study J. Am. Coll. Nutr. 2016, 35:621-626.
  117. F. Sofi, L. Ghiselli, M. Dinu, A. Whittaker, G. Pagliai, F. Cesari, C. Fiorillo, M. Becatti, R. Tallarico, A. Casini and S. Benedettelli Consumption of buckwheat products and cardiovascular risk profile: a randomized single-blinded crossover trial J. Nutr. Food Sci. 2016, 6:3.
  118. F. Sofi, M. Dinu, G. Pagliai, F. Cesari, R. Marcucci and A. Casini Mediterranean vs. vegetarian diet for cardiovascular prevention (the CARDIVEG study): study protocol for a randomized controlled trial Trials  2016, 17:233.
  119. F. Sofi and M. Dinu Nutrition and prevention of chronic-degenerative diseases Agr. Agr. Sci. Proc. 2016,  8:713–717.
  120. A. Whittaker, M. Dinu, F. Cesari, AM. Gori, C. Fiorillo, M. Becatti, A. Casini, R. Marcucci, S. Benedettelli and F. Sofi A Khorasan wheat-based replacement diet improves risk profile of patients with type 2 diabetes mellitus (T2DM): a randomized crossover trial Eur. J. Nutr. 2016, doi: 10.1007/s00394-016-1168-2.
  121. M. Dinu, R. Abbate, GF. Gensini, A. Casini and F. Sofi Vegetarian, vegan diets and multiple health outcomes: a systematic review with meta-analysis of observational studies Crit. Rev. Food Sci. Nutr. 2016 doi: 10.1080/10408398.2016.1138447.
  122. Fontani F, Domazetovic V, Marcucci T, Vincenzini MT, Iantomasi T. Tumor Necrosis Factor-Alpha Up-Regulates ICAM-1 Expression and Release in Intestinal Myofibroblasts by Redox-Dependent and -Independent Mechanisms. Cell Biochem. 2016, 117(2):370-81.
  123. Ceni E, Mello T, Polvani S, Vasseur-Cognet M, Tarocchi M, Tempesti S, Cavalieri D, Beltrame L, Marroncini G, Pinzani M, Milani S, Galli A. The orphan nuclear receptor COUP-TFII coordinates hypoxia-independent proangiogenic responses in hepatic stellate cells J Hepatol. 2016, Nov 17. [Epub ahead of print]
  124. Fanni E, Castellini G, Corona G, Boddi V, Ricca V, Rastrelli G, Fisher AD, Cipriani S, Maggi M. The Role of Somatic Symptoms in Sexual Medicine: Somatization as Important Contextual Factor in Male Sexual Dysfunction J Sex Med. 2016,  9: 1395–1407.
  125. R. Cascella, C. Capitini, G. Fani, C.M. Dobson, C. Cecchi, F. Chiti Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies J. Biol. Chem. 2016, 291: 19437-48.
  126. Vaszkó T, Papp J, Krausz C, Casamonti E, Géczi L, Olah E Discrimination of deletion and duplication subtypes of the deleted in azoospermia gene family in the context of frequent interloci gene conversion PLoS One 2016, 11:e0163936.
  127. E. Cinelli, L. Iovino, F. Bongianni, T. Pantaleo and D. Mutolo GABAA- and glycine-mediated inhibitory modulation of the cough reflex in the caudal nucleus tractus solitarii of the rabbit Am. J. Physiol. Lung Cell. Mol. Physiol. 2016, 311:L570-L580.
  128. D. Mutolo, E. Cinelli, L. Iovino, T. Pantaleo and F. Bongianni Downregulation of the cough reflex by aclidinium and tiotropium in awake and anesthetized rabbits J. Pulm. Pharmacol. Ther. 2016, 38:1-9.
  129. D. Lana, L. Iovino, D. Nosi, G.L.Wenk and M.G. Giovannini The neuron-astrocyte-microglia triad involvement in neuroinflammaging mechanisms in the CA3 hippocampus of memory-impaired old rats Exp. Gerontol. 2016, 83:71-88.
  130. Azzari C, Cortimiglia M, Nieddu F, Moriondo M, Indolfi G, Mattei R, Zuliani M, Adriani B, Degl'Innocenti R, Consales G, Aquilini D, Bini G, Di Natale ME, Canessa C, Ricci S, de Vitis E, Mangone G, Bechini A, Bonanni P, Pasinato A, Resti M. Pneumococcal serotype distribution in adults with invasive disease and in carrier children in Italy: Should we expect herd protection of adults through infants' vaccination? Hum Vaccin Immunother. 2016, 12(2):344-50.
  131. C. Sassoli, F. Pierucci, A. Tani, A. Frati, F.Chellini, G. Anderloni, F.Matteini, S. Zecchi-Orlandini and E.Meacci. The autocrine/paracrine action of bone-marrow-derived mesenchymal stromal cells required SphK1/S1P/S1P1 axis.  Stem Cells 2016, [Second revision]
  132. F. Pierucci, A. Frati, R. Squecco, E. Lenci, C. Vicenti, J. Slavik, F. Francini, M. Machala and E. Meacci. Non-dioxin-like organic toxicant PCB153 alters Cx43-formed Gap junction function in liver progenitor cells trough the modulation of sphingolipid metabolism. Arch Toxicol. 2016, 91(2):749-760.
  133. A. Frati, B. Ricci, F. Pierucci, S. Nistri, D. Bani and E. Meacci Role of sphingosine kinase/s1p axis in ecm-remodeling of cardiac cells elicited by the  hormone relaxin. Mol Endocrinol. 2015, 29(1):53-67.
  134. C.D. Hart, F. Galardi, M. Pestrin, F. De Luca, E. Risi, A. Di Leo Using CTCs for pharmacogenomic analysis. Pharmacol Res. 2016, 106-92.
  135. M.E. Manni, S. Rigacci, E. Borchi, V. Bargelli, C. Miceli, C. Giordano, L. Raimondi, C. Nediani Monoamine oxidase is overactivated in left and right ventricles from ischemic hearts: an intriguing therapeutic target. Ox. Med. Cell. Long. 2016,:4375418.
  136. R. Grande, C. Natoli, F. Ciancola, D. Gemma, A. Pellegrino, I. Pavese, C. Garufi, L. Di Lauro, D. Corsi, D. Signorelli, I. Sperduti, G. Cortese, E. Risi, F. Morano, D. Sergi, C. Signorelli, E.M. Ruggeri, G. Zampa, M. Russano, T. Gamucci Treatment of Metastatic Colorectal Cancer Patients ≥ 75 Years Old in Clinical Practice: A Multicenter Analysis.  PLoS ONE 2016, 11-e0157751.
  137. I. Luccarini, D. Pantano, P. Nardiello, L. Cavone, A. Lapucci, C. Miceli, C. Nediani, M. Stefani and F. Casamenti The polyphenol oleuropein aglycone modulates the PARP1-SIRT1 interplay: an in vitro and in vivo study. J. Alz. Dis. 2016, 54:737-50
  138. E. Del Poggetto, L. Gori, F. Chiti Biophysical analysis of three novel profilin-1 variants associated with amyotrophic lateral sclerosis indicates a correlation between their aggregation propensity and the structural features of their globular state. Biol. Chem. 2016, 397:927-37.
  139. C. Grossi, I. Luccarini, S. Rigacci, D. Pantano, E. Coppi, A.M. Pugliese, T. Ed Dami, A. Berti, M. Stefani & F. Casamenti Oleuropein aglycone protects a Tg mouse model against pE3-Aß deposition: biochemical, epigenetic and functional correlates. Neurobiol. Aging 2015, 36:648-63.
  140. F. Casamenti, C. Grossi, S. Rigacci, D. Pantano, I. Luccarini and M. Stefani Oleuropein aglycone: a possible drug against degenerative conditions. In vivo evidence of its effectiveness against Alzheimer’s disease J. Alz. Dis. 2015, 45:679-88. I
  141. S. Rigacci, C. Miceli, C. Nediani, A. Berti and M. Stefani Oleuropein aglycone induces autophagy in exposed cells: a mechanistic study. Oncotarget 2015, 6:35344-57.
  142. Fisher AD, Castellini G, Casale H, Fanni E, Bandini E, Campone B, Ferruccio N, Maseroli E,Boddi V, Dèttore D, Pizzocaro A, Balercia G, Oppo A, Ricca V, Maggi M. Hypersexuality, Paraphilic Behaviors, and Gender Dysphoria in Individuals with Klinefelter's Syndrome.  J Sex Med. 2015, 12:2413-24.
  143. Boddi V, Fanni E, Castellini G, Fisher AD, Corona G, Maggi M. Conflicts Within the Family and Within the Couple as Contextual Factors in the Determinism of Male Sexual Dysfunction J Sex Med. 2015, 12:2425-35.
  144. Krausz C, Escamilla AR, Chianese C Genetics of male infertility: from research to clinic Reproduction 2015, 150:R159-74.
  145. Chianese C, Fino MG, Riera Escamilla A, López Rodrigo O, Vinci S, Guarducci E, Daguin F, Muratori M, Tamburrino L, Lo Giacco D, Ars E, Bassas L, Costa M, Pisatauro V, Noci I, Coccia E, Provenzano A, Ruiz-Castañé E, Giglio S, Piomboni P, Krausz C Comprehensive investigation in patients affected by sperm macrocephaly and globozoospermia Andrology 2015, 3(2):203-12.
  146. E. Del Poggetto, M. Tanturli, N. Ben-Califa, A. Gozzini, I. Tusa, G. Cheloni, I. Marzi, M.G. Cipolleschi, Y. Kashman, D. Neumann, E. Rovida, P. Dello Sbarba Salarin c inhibits the maintenance of chronic myeloid leukemia progenitor cells Cell Cycle 2015, 14:3146-54.
  147. E. Del Poggetto, F. Chiti, F. Bemporad The folding process of human profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis Sci. Rep. 2015, 31: 5.
  148. E. Del Poggetto, F. Bemporad, F. Tatini, F. Chiti) Mutations of profilin-1 associated with amyotrophic lateral sclerosis promote aggregation due to structural changes of its native state ACS Chem. Biol. 2015, 10:2553-63.
  149. M. Lambertini, AR. Ferreira, F. Poggio, F. Puglisi, A. Bernardo, F. Montemurro, E. Poletto, E. Pozzi, V. Rossi, E. Risi, A. Lai, E. Zanardi, V. Sini, S. Ziliani, G. Minuti, S. Mura, D. Grasso, A. Fontana, L. Del Mastro Patterns of Care and Clinical Outcomes of First-Line Trastuzumab-Based Therapy in HER2-Positive Metastatic Breast Cancer Patients Relapsing After (Neo)Adjuvant Trastuzumab: An Italian Multicenter Retrospective Cohort Study. Oncologist 2015, 20-880.
 
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